Obesity prevented in mice fed high-fat diet

Obesity prevented in mice fed high-fat diet

Researchers at Washington University School of Medicine in St. Louis have identified a way to prevent fat cells from growing larger, a process that leads to weight gain and obesity. By activating a pathway in fat cells in mice, the researchers found they could feed the animals a high-fat diet without making them obese.

Obesity, excess weight in U.S. continue upswing

Obesity and excess weight, and their negative impact on health, have become a significant focus for health-care experts in recent years. But new research at Washington University School of Medicine shows that an escalation in the number of those considered obese or overweight in the U.S. continues, signaling an ongoing upward swing in chronic health conditions as well.

National study examines ways federal policy can impact childhood, adolescent obesity

A tax on sugar-sweetened beverages such as sodas, energy drinks, sweet teas and sports drinks could reduce obesity in adolescents, and exercise promotion such as after-school physical activity programs could impact younger children in the fight against fat. Those are the findings of a new national study co-authord by Ross Brownson, PhD, professor at the Brown School at Washington University in St. Louis.

Glaucoma drug helps restore vision loss linked to obesity

Vision researchers from 38 clinical sites, including the School of Medicine, have found that the eyesight of patients with an unusual vision disorder linked to obesity improves twice as much if they take a glaucoma drug and lose a modest amount of weight than if they only lose weight. Neuro-ophthalmologist Gregory Van Stavern, MD, led the study in St. Louis.

Public health conference ​​​to address obesity

The obesity epidemic and how science may be able to impact it is the focus of the upcoming annual conference of the Institute for Public Health at Washington University in St. Louis. Graham Colditz, MD, DrPH, deputy director of the Institute for Public Health and a disease prevention expert at Siteman Cancer Center, will deliver the keynote address.

Altering mix of gut microbes prevents obesity, but diet remains key factor

The mix of microbes living inside the gut can protect against obesity, but a healthy diet is critical, according to School of Medicine scientists who transplanted intestinal microbes from obese and lean twins into mice and fed the animals different diets. Pictured are researchers Vanessa Ridaura, a graduate student, and Jeffrey I. Gordon, MD, director of the Center for Genome Sciences and Systems Biology.

Obesity, aging genes may play role in arthritis

Studying gene activity in tissue removed from injured knees, researchers at Washington University School of Medicine in St. Louis have found that genes related to obesity and aging may contribute to the development of osteoarthritis, the most common knee disorder and the most common disorder in all of the joints.