New target for treating diabetes and obesity

Researchers at Washington University School of Medicine in St. Louis have identified a potential target for treating diabetes and obesity. Studying mice, they found that when the target protein was disabled, the animals became more sensitive to insulin and were less likely to get fat.

Protein may play role in obesity, diabetes, aging

Researchers at Washington University School of Medicine in St. Louis, led by Philip Stahl, PhD, professor of cell biology and physiology have identified a potent regulator of sensitivity to insulin, the hormone that controls blood sugar levels. The new findings may help scientists find better treatments for type 2 diabetes, obesity and other health problems caused by the body’s inability to properly regulate blood sugar.

WU studies obesity, cancer link with $9.2 million grant

Researchers at Washington University School of Medicine in St. Louis have been awarded a $9.2 million grant from the National Cancer Institute to study the relationship between obesity and cancer. The five-year grant will fund the new Transdisciplinary Research on Energetics and Cancer Center. Led by Graham A. Colditz, MD, PhD, the Center’s researchers will study the effect of diet, weight, physical activity and the environment on cancer and cancer survivorship.

Risk for alcoholism linked to risk for obesity

Addiction researchers at Washington University School of Medicine in St. Louis have found that a risk for alcoholism also may put individuals at risk for obesity, and the association between a family history of alcoholism and obesity risk has become more pronounced in recent years.  

Research in twins defines shared features of the human gut microbial communities: variations linked to obesity

Trillions of microbes make their home in the gut, where they help to break down and extract energy and nutrients from the food we eat. Yet, scientists have understood little about how this distinctive mix of microbes varies from one individual to the next. Now, researchers at the School of Medicine have discovered that each individual carries a unique collection of bacteria, although the communities are more similar among family members.

First U.S. incision-free procedure for obesity performed at Washington University

Photo by Tim ParkerSreenivasa Jonnalagadda, M.D., and J. Christopher Eagon, M.D., performing the first TOGA procedure in the United States.Doctors at the School of Medicine have performed the first non-surgical procedure in the United States that restricts the size of the stomach to treat obesity. The investigational procedure was performed under direct endoscopic visualization with specialized instruments passed into the stomach through the mouth. The first U.S. patient received the treatment on July 23 at Barnes-Jewish Hospital in St. Louis.