Researchers at the School of Medicine have shown that levels of tau protein can be reduced – and some of the neurological damage caused by tau even reversed – by a synthetic molecule that targets genetic instructions. The findings are important for Alzheimer’s and other neurological diseases.
Jason S. Goldfeder, MD, a revered teacher in the Division of Medical Education of the Department of Medicine at the School of Medicine, died Dec. 9, 2015, following a 12-year battle with amyotrophic lateral sclerosis (ALS).
Timothy M. Miller, MD, PhD, a leading researcher in the neurodegenerative disorder amyotrophic lateral sclerosis (ALS), has been named the David Clayson Professor of Neurology at the School of Medicine. The professorship was established in 2001 through a bequest from David Clayson, PhD, to support innovative research into treatments for ALS.
Genetic mutations may cause more cases of amyotrophic lateral sclerosis (ALS) than scientists previously had realized, according to researchers. Shown are study authors Janet Cady, a PhD candidate, and Matthew Harms, MD, assistant professor of neurology at the School of Medicine.
Digoxin, a medication that has been used to treat heart failure, may be adaptable for the treatment of amyotrophic lateral sclerosis (ALS), a progressive, paralyzing disease, suggests new research at the School of Medicine.
Thomas H. Steinberg, MD, associate professor of medicine, died Sunday, June 16, 2013, in St. Louis of complications from amyotrophic lateral sclerosis (ALS), often referred to as Lou Gehrig’s Disease.
An investigational treatment for an inherited form of Lou Gehrig’s disease has passed an early phase clinical trial for safety, researchers at the School of Medicine and Massachusetts General Hospital report. A mutated protein that causes an inherited form of Lou Gehrig’s disease leads to clumps in the human cells, which are pictured.
Alison Goate, PhD, has been named director of the Hope Center for Neurological Disorders, a partnership between Washington University School of Medicine in St. Louis and Hope Happens, a nonprofit foundation that supports research into neurodegenerative disorders.