AMD3100

Red areas of the circled leg in the right image show increased blood flow due to angiogenic cells.To speed healing at sites of injury – such as heart muscle after a heart attack or brain tissue after a stroke – doctors would like to be able to hasten the formation of new blood vessels. One promising approach is to “mobilize” patients’ blood vessel-forming cells, called angiogenic cells, so these cells can reach the injured area. Recently, researchers at the School of Medicine demonstrated that a drug called AMD3100 can mobilize angiogenic cells from bone marrow of human patients in a matter of hours.

Red areas of the circled leg in the right image show increased blood flow due to angiogenic cells.To speed healing at sites of injury – such as heart muscle after a heart attack or brain tissue after a stroke – doctors would like to be able to hasten the formation of new blood vessels. One promising approach is to “mobilize” patients’ blood vessel-forming cells, called angiogenic cells, so these cells can reach the injured area. Recently, researchers at Washington University School of Medicine in St. Louis demonstrated that a drug called AMD3100 can mobilize angiogenic cells from bone marrow of human patients in a matter of hours.