Study in mice suggests sleep problems may be early sign of Alzheimer’s

Sleep disruptions may be among the earliest indicators of the start of Alzheimer’s disease, scientists at Washington University School of Medicine in St. Louis report this week in Science Translational Medicine. David M. Holtzman, MD, the Andrew B. and Gretchen P. Jones Professor and head of the Department of Neurology, is the study’s author.

Washington People: Randall Bateman

Randall Bateman, MD, had no intention of becoming a doctor when he enrolled as an undergraduate at Washington University in St. Louis. As a faculty member at the School of Medicine since 2006, Bateman now focuses his research on Alzheimer’s disease.

Falls may be early sign of Alzheimer’s

Falls and balance problems may be early indicators of Alzheimer’s disease, researchers at Washington University School of Medicine in St. Louis report July 17, 2011, at the Azheimer’s Association International Conference on Alzheimer’s Disease in Paris.

Alzheimer’s patients can’t effectively clear sticky plaque component

Neurologists finally have an answer to one of the most important questions about Alzheimer’s disease: Do rising brain levels of a plaque-forming substance mean patients are making more of it or that they can no longer clear it from their brains as effectively? A new study by Randall Bateman, MD, assistant professor of neurology, shows clearance is impaired in Alzheimer’s patients.

Researchers identify genetic marker of aggressive Alzheimer’s disease

An international team of Alzheimer’s disease experts, led by Washington University School of Medicine in St. Louis, has uncovered a gene variation that appears to predict the rate at which Alzheimer’s disease will progress. Whereas previous studies have focused on factors that influence the risk for developing Alzheimer’s, the new research points to a way to determine how rapidly the disease will progress.