‘Blink’ and you won’t miss amyloids

‘Blink’ and you won’t miss amyloids

Tiny protein structures called amyloids are key to understanding certain devastating age-related diseases, but they are so minuscule they can’t be seen using conventional microscopic methods. A team of engineers at Washington University in St. Louis has developed a new technique that uses temporary fluorescence, causing the amyloids to flash or “blink”, allowing researchers to better spot these problematic proteins.