Fuzhong Zhang, an expert in synthetic biology at the McKelvey School of Engineering, is investigating how genetically identical cells manage to act so differently. The answer may have implications for antibiotic persistence.
A new study led by Petra Levin in Arts & Sciences suggests that triclosan exposure may inadvertently drive bacteria into a state in which they are able to tolerate normally lethal concentrations of antibiotics — including those antibiotics that are commonly used to treat urinary tract infections.
Buoyed by a $5.1 million grant, researchers at Washington University School of Medicine in St. Louis will study novel strategies to reduce infections acquired in health-care settings and to limit the spread of dangerous antibiotic-resistant bacteria. The funding is part of $26 million awarded by the Centers for Disease Control and Prevention (CDC) to five academic medical centers as part of a patient-safety effort known as the Prevention Epicenters Program.
ICU patients who are bathed daily with antiseptic wipes have significantly lower rates of bloodstream infections and are less likely to acquire antibiotic-resistant bacteria on the skin, according to a new study from researchers including David Warren, MD, medical director for infection prevention at the School of Medicine.
Antibiotics that doctors typically prescribe for sinus infections do not reduce symptoms any better than an inactive placebo, according to Jay F. Piccirillo, MD, and his co-investigators at Washington University School of Medicine in St. Louis. Instead of giving antibiotics, the researchers suggest treating symptoms, such as pain, cough and congestion, along with watchful waiting to see whether further treatment is necessary.