Margolis receives grant for research on blinding diseases

Todd P. Margolis, MD, PhD, the Alan A. and Edith L. Wolff Distinguished Professor and head of the Department of Ophthalmology and Visual Sciences, has been awarded a $115,000 grant by Research to Prevent Blindness to support research into the causes, treatment and prevention of blinding diseases.

Gender influences symptoms of genetic disorder

Researchers at Washington University School of Medicine in St. Louis have identified a patient’s gender as a clear and simple guidepost to help health care providers anticipate some of the otherwise unpredictable effects of neurofibromatosis type 1, a childhood genetic disorder.

Altering eye cells may one day restore vision

Doctors may one day treat some forms of blindness by altering the genetic program of the light-sensing cells of the eye, according to School of Medicine scientists. Working in mice with a disease that causes gradual blindness, the researchers reprogrammed the cells in the eye that enable night vision.

Gene scan helps identify cause of inherited blindness

Scientists at Washington University School of Medicine in St. Louis have scanned the entire genome of mice for genes that help build photoreceptors, the light-sensing cells of the eye. The results have already helped researchers identify the gene that causes a form of retinitis pigmentosa, a type of inherited blindness in humans.

Birds ‘one-up’ humans in ability to see color

Researchers at the School of Medicine have peered deep into the eye of the chicken and found a masterpiece of biological design. They plan follow-up studies that could eventually provide helpful insights for scientists seeking to use stem cell and other techniques to treat the nearly 200 genetic disorders that can cause various forms of blindness.