Fragile X syndrome, an inherited cause of autism and intellectual disability, can have consequences even for carriers of the disorder who don’t have full-blown symptoms. Researchers at Washington University School of Medicine in St. Louis have identified a potential target for treatment for fragile X carriers.
New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain. These connections, or synapses, allow nerve cells to transmit and process information involved in thinking and moving the body. Pictured is the study’s senior author, Azad Bonni, MD, PhD.
An odd feature of nerve cells may be linked to several forms of inherited intellectual disability, Azad Bonni, MD, PhD, (pictured) and other School of Medicine researchers have learned. Further research eventually may help in the development of drugs to treat intellectual disability.
A rare, inherited form of mental retardation has led scientists at the School of Medicine to three important “travel agents” at work in the developing brain. The agents make it possible for brain neurons to travel from where they are born to other brain regions where they will permanently reside.
Azad Bonni, MD, PhD, currently professor of neurobiology at Harvard Medical School, will be the next head of the Department of Anatomy and Neurobiology at Washington University School of Medicine in St. Louis.