Damage to brain ‘hubs’ causes extensive impairment

Injuries to six brain areas are much more devastating to patients’ abilities to think and adapt to everyday challenges than damage to other parts of the brain, scientists at Washington University School of Medicine have learned.

Alzheimer’s plaques disrupt brain networks

Scientists studying the way Alzheimer’s disease takes root in the brain have identified important new similarities between a mouse model and human Alzheimer’s. Researchers at Washington University School of Medicine in St. Louis have shown that brain plaques in mice are associated with disruption of the ability of brain regions to network with each other.