Amit Pathak, a mechanical engineer at Washington University in St. Louis who specializes in mechanobiology, plans to take a closer look at various aspects of cell group behavior — and their implications for diseases such as cancer — with a prestigious five-year, $1.9 million grant for early-stage investigators from the National Institutes of Health (NIH).
Human cells have a way of detecting and mending DNA damage caused by some common chemotherapy drugs, according to a new study from the School of Medicine. The findings could have important implications for treating cancer.
Privately insured children and those with Medicaid at the time of a cancer diagnosis experience largely similar survival trends, with slight evidence for an increased risk of cancer death in children who were uninsured at diagnosis, finds a new study from the Brown School at Washington University in St. Louis.
Researchers from Washington University in St. Louis and St. Jude Children’s Research Hospital in Memphis made a discovery that uncovers the molecular logic of how dividing cells are stopped in their tracks. The team zeroed in on a specific protein, whose job is to stop a cell from dividing or to slow the division.
For more than 80 years, scientists have thought that cancer cells fuel their explosive growth by soaking up glucose from the blood, using its energy and atoms to crank out duplicate sets of cellular components. But is this really true? Work in a metabolomics laboratory at Washington University in St. Louis suggests not.
Engineers at Washington University in St. Louis use nanoparticle technology, applied to a drug found in most people’s medicine cabinets, to chemically alter a cancer tumor and stop its growth.
Breast cancer takes a daunting toll on all women, but it hits younger women especially hard, finds a new study from the Brown School. Women aged 18-44 with a history of breast cancer reported a lower health-related quality of life than older survivors, highlighting the impact of breast cancer on the physical and mental health of younger women.
Mistrust toward breast cancer treatment and the health care system at large were expressed by African Americans who participated in Chicago focus groups, suggests new research led by an expert on the health of vulnerable populations at the Brown School at Washington University in St. Louis.
In a new analysis, researchers at the School of Medicine have shed light on the hereditary elements across 12 cancer types — showing a surprising inherited component to stomach cancer and providing some needed clarity on the consequences of certain types of mutations in well-known breast cancer susceptibility genes BRCA1 and BRCA2.
New research, led by Li Ding, PhD, shows that current genome analysis approaches systematically miss detecting a certain type of complex mutation in cancer patients’ tumors. A significant percentage of these complex mutations are found in well-known cancer genes that could be targeted by existing drugs, potentially expanding the number of cancer patients who may benefit.