Depression and behavioral changes may occur before memory declines in people who will go on to develop Alzheimer’s disease, according to new research at the School of Medicine led by senior author Catherine M. Roe, PhD.

School of Medicine researchers have shown that several markers for presymptomatic Alzheimer’s disease identified in recent years are accurate predictors of Alzheimer’s years before symptoms develop. Catherine Roe, PhD, says researchers found no differences in the accuracy of the biomarkers.