Pretesting cervical tumors could inform treatment

Doctors at the School of Medicine have shown that testing cervical tumors before treatment for vulnerability to chemotherapy predicts whether patients will do well or poorly with standard treatment. The study supports the future possibility of personalized medicine for cervical cancer, a tumor normally addressed with a one-size-fits-all approach. Pictured is a cervical tumor visible on a PET/CT scan.

Mouse model paves way for lung cancer studies

Lung tumors from mutant mice show an abundance of abnormal, undifferentiated cells.Often mice are used to investigate cancer because their accelerated life spans allow discoveries to be made in a few months. But most strains of mice stay relatively free of lung tumors, even when exposed to heavy tobacco smoke, so there has been a shortage of models suitable for studying tobacco smoke-induced lung cancer. Now, cancer researchers at the School of Medicine have developed a strain of mice that readily develops lung tumors that have the same genetic mutations found in human lung tumors.

Mouse model paves way for lung cancer studies

Lung tumors from mutant mice show an abundance of abnormal, undifferentiated cells.Often mice are used to investigate cancer because their accelerated life spans allow discoveries to be made in a few months. But most strains of mice stay relatively free of lung tumors, even when exposed to heavy tobacco smoke, so there has been a shortage of models suitable for studying tobacco smoke-induced lung cancer. Now, cancer researchers at Washington University School of Medicine in St. Louis have developed a strain of mice that readily develops lung tumors that have the same genetic mutations found in human lung tumors.