New research by Daniel Link, MD, and colleagues at The Genome Institute at Washington University has revealed that mutations that accumulate randomly as a person ages can play a role in a fatal form of leukemia that develops after treatment for another cancer.
The National Cancer Institute has awarded two major grants totaling $26 million to leukemia researchers and physicians at the School of Medicine. The funding has the potential to lead to novel therapies for leukemia that improve survival and reduce treatment-related side effects. Pictured are cancer cells from a patient with acute myeloid leukemia.
In research that one day could improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in the bone marrow to nurture different types of blood stem cells.
Hundreds of mutations exist in leukemia cells at the time of diagnosis but nearly all occur randomly as a part of normal aging and are not related to cancer, new research at Washington University School of Medicine shows.