Early-stage diabetic heart disease mimicked in mouse hearts

The brighter signal over the transgenic heart indicates fat uptake and metabolism are greatly increased.Heart disease is the leading cause of death among the more than 13 million diabetics in the United States. Researchers at the School of Medicine have found that in mice whose heart muscles take up high amounts of fat, the heart fills abnormally after each contraction, a condition that is consistent with the first stage of heart dysfunction in human diabetics.

Early-stage diabetic heart disease mimicked in mouse hearts

The brighter signal over the transgenic heart indicates fat uptake and metabolism are greatly increased.Heart disease is the leading cause of death among the more than 13 million diabetics in the United States. Researchers at Washington University School of Medicine in St. Louis have found that in mice whose heart muscles take up high amounts of fat, the heart fills abnormally after each contraction, a condition that is consistent with the first stage of heart dysfunction in human diabetics.