Studying mice, scientists at Washington University School of Medicine in St. Louis have identified two signaling molecules that are required for the proper development of a part of the inner ear called the cochlea. The study contributes to the understanding of inner ear development, a first step toward the goal of being able to recover lost hearing.
Studying mice and humans, researchers at Washington University School of Medicine in St. Louis and their collaborators in Paris have identified two proteins that are required to maintain a supply of stem cells in the developing kidney. The work is a small step toward the future goal of growing kidney stem cells in the lab.
Providing clues to deafness, researchers at Washington University School of Medicine in St. Louis have identified a gene that is required for proper development of the mouse inner ear. In humans, this gene, known as FGF20, is located in a portion of the genome that has been associated with inherited deafness in otherwise healthy families.