Combination treatment in mice shows promise for fatal neurological disorder in kids
Batten disease is a rare but fatal neurological disorder that typically strikes young children. Working in mice with the infantile form of the disease, scientists have discovered dramatic improvements in life span and motor function by treating the animals with gene therapy and bone marrow transplantation.
$3.7 million trial uses genes to balance risks, benefits of blood thinner
A five-year, $3.7 million clinical trial will investigate how to balance the benefits and risks of warfarin, a drug that helps prevent potentially deadly blood clots. The multicenter study, led by researchers at Washington University School of Medicine in St. Louis, will evaluate customized warfarin dosage based on patient genetics and will test which range of blood clotting is optimal in orthopedic patients.