Scientists’ picture of how a gene strongly linked to Alzheimer’s disease harms the brain may have to be revised, researchers at the School of Medicine have found. Washington University’s David M. Holtzman, MD, says leading researchers recently agreed that targeting this gene is a promising approach for gaining a better understanding of and improving treatments for the disease.
Doctors may one day treat some forms of blindness by altering the genetic program of the light-sensing cells of the eye, according to School of Medicine scientists. Working in mice with a disease that causes gradual blindness, the researchers reprogrammed the cells in the eye that enable night vision.
Soil bacteria and bacteria that cause human diseases have recently swapped at least seven antibiotic-resistance genes, researchers at Washington University School of Medicine report on Aug. 31 in Science.
When a child has autism, siblings are also at risk for the disorder. New research from Washington University School of Medicine in St. Louis shows that the genetic reach of the disorder often extends to half siblings as well. The discovery is giving scientists new clues to how autism is inherited.
Scientists at Washington University School of Medicine in St. Louis are playing a leading role in an international collaboration dedicated to understanding genes that contribute to inflammatory bowel disease.
A new study shows that the environment interacts with DNA in ways that are difficult to predict, even in simple organisms like single-celled yeast, which complicates the prospects for personalized medicine.
Scientists at Washington University School of Medicine in St. Louis have scanned the entire genome of mice for genes that help build photoreceptors, the light-sensing cells of the eye. The results have already helped researchers identify the gene that causes a form of retinitis pigmentosa, a type of inherited blindness in humans.
Ten patients ranging in age from 7-23 came to the School of Medicine in August for testing and evaluation at the first-ever multidisciplinary clinic for Wolfram syndrome.
Improving the lives of infants and children with developmental disabilities will be the focus of Washington University’s new Intellectual and Developmental Disabilities Research Center (WUIDDRC).
A genome-wide study into the genetic roots of alcoholism has identified several areas of DNA that appear to contribute to the disease. But researchers say those genes make relatively modest contributions to overall risk of alcoholism.