Researchers led by John F. DiPersio, MD, PhD, at the School of Medicine have designed a way to mitigate graft-versus-host disease, a common and often life-threatening complication of bone marrow transplants that are used to treat leukemia and other blood cancers. The method also employs a molecular imaging tool to help doctors identify patients most likely to develop this dangerous condition.
Every year, Siteman Cancer Center hosts a gathering for former bone marrow transplant patients, their families and the staff who helped care for them. It’s a celebration of survival. And every year, John F. DiPersio, MD, PhD, chief of the Division of Oncology, looks out over the audience and marvels. From the lab to the clinic, DiPersio’s work is guided by his commitment to his patients.
Studying leukemia in mice, John F. DiPersio, MD, PhD, and his colleagues at Washington University School of Medicine in St. Louis, have reduced a life-threatening complication of stem cell transplants, the only curative treatment when leukemia returns.