Development of gut microbes and gut immunity linked
Studying twins from birth through age 2, scientists at Washington University School of Medicine in St. Louis have shown that the gut’s immune system develops in sync with the gut’s tens of trillions of microbes. The findings have implications for understanding healthy growth and, potentially, the origins of various immune disorders.
Preemies’ gut bacteria reveal vast scope of antibiotic resistance
A new Washington University School of Medicine study reveals extensive antibiotic resistance in the gut bacteria of premature infants. The researchers say these findings support the push to minimize routine use of antibiotics in these patients.
Mimicking diet changes of global travel reveals clues to gut health
With the growing understanding of the importance of gut bacteria in human health, researchers at the School of Medicine studied gut motility, measuring the transit time of food moving through the gastrointestinal tract in mice in a way that mimicked the dietary effects of world travel. The study demonstrates ways to uncover how even a single ingredient, such as turmeric, can affect health through interactions of diet and gut microbes.
Viruses flourish in guts of healthy babies
Bacteria aren’t the only non-human invaders to colonize the gut shortly after a baby’s birth. Viruses also set up house there, according to new research led by Lori Holtz, MD, at Washington University School of Medicine in St. Louis.
A person’s diet, acidity of urine may affect susceptibility to UTIs
The acidity of urine — as well as the presence of small molecules related to diet — may influence how well bacteria can grow in the urinary tract, a new study shows. The research, led by Jeffrey Henderson, MD, PhD, at Washington University School of Medicine in St. Louis, may have implications for treating urinary tract infections, which are among the most common bacterial infections worldwide.
Genome of a Major Member of Gut Bacteria Sequenced: Clues to Beneficial Relationships Between Humans and Microorganisms
Researchers at Washington University School of Medicine in St. Louis have completed sequencing the genome of Bacteroides thetaiotaomicron, one of the most prevalent bacteria that live in the human intestine. The results appear in the March 28 issue of the journal Science.