hypertension

Angela L. Brown, MD, associate professor of medicine, leads the Hypertension Clinic at Washington University School of Medicine. Brown has devoted her career to helping patients control their hypertension and to training medical professionals in how to care for such patients.

Led by Jasvindar Singh, MD, doctors at Washington University School of Medicine in St. Louis are seeking volunteers for a clinical trial testing an investigational device in patients with severe high blood pressure that can’t be controlled with aggressive medical treatments.

Researchers at Washington University School of Medicine in St. Louis are studying people age 60 and older to determine whether augmenting medication for depression with a second drug might help older patients break free of clinical depression. Both study drugs are FDA-approved therapies for depression in younger adults, but the benefits need to be examined in older adults. 

New HIV therapies have contributed to a decrease in AIDS deaths, but physicians suspected the more potent medications led to symptoms characteristic of metabolic syndrome. However, now researchers at the School of Medicine have found that the rate of metabolic syndrome in HIV-infected patients is virtually identical to that in uninfected people.

New HIV therapies have contributed to a decrease in AIDS deaths, but physicians suspected the more potent medications led to symptoms characteristic of metabolic syndrome. However, now researchers at Washington University School of Medicine in St. Louis have found that the rate of metabolic syndrome in HIV-infected patients is virtually identical to that in uninfected people. Furthermore, the type or duration of HIV therapy did not affect the rate of metabolic syndrome.

Hearts with muscle thickening (left) get less energy because of their reduced fat metabolism.”The heart is the single most energy-consuming organ per weight in the body,” says Lisa de las Fuentes, M.D. Under some conditions this energy-hungry organ is prone to defects in its energy metabolism that contribute to heart disease, according to research published in the Journal of Nuclear Cardiology by de las Fuentes and colleagues at the School of Medicine.

Echocardiograms show that the thickness of left ventricular (LV) walls in the hypertrophied heart (left) are nearly twice that of the normal heart.”The heart is the single most energy-consuming organ per weight in the body,” says Lisa de las Fuentes, M.D. Under some conditions this energy-hungry organ is prone to defects in its energy metabolism that contribute to heart disease, according to research published in the Journal of Nuclear Cardiology by de las Fuentes and colleagues at Washington University School of Medicine in St. Louis.

Studying elderly people with mild to moderately elevated blood pressure, researchers at the School of Medicine have found that exercise is just as effective as blood pressure medicine at reducing heart mass and the thickness of the heart wall. Exercise also provided benefits that blood pressure medicine did not, such as lowering an individual’s risk of developing diabetes.