Drastically cutting calories lowers some risk factors for age-related diseases​​

The largest study to date of sustained calorie reduction in adults shows that it does not produce all of the metabolic effects associated with longevity that have been found in animal studies. Severely cutting calorie intake, however, did appear to lower the risk of cardiovascular disease and make people more sensitive to insulin, according to John O. Holloszy, MD, principal investigator at the study’s Washington University clinical site.