Aging and longevity tied to specific brain region in mice

The protein SIRT1 in the brain is tied into a mechanism that allows animals to survive when food is scarce, according to a new study at Washington University School of Medicine in St. Louis. The research suggests that SIRT1 may be involved with the life span-increasing effect of low-calorie diets, they report.

Cryer receives American Diabetes Association’s Renold Award

Philip E. Cryer, MD, will receive the American Diabetes Association’s Albert Renold Award at the organization’s 70th Scientific Sessions in Orlando, Fla. The Albert Renold Award is presented to an individual whose career is distinguished by outstanding achievements in the training of diabetes research scientists and the facilitation of diabetes research. 

Unusual three-drug combo inhibits growth of aggressive tumors

An experimental anti-cancer regimen combined a diuretic, a Parkinson’s disease medication and a drug ordinarily used to reverse the effect of sedatives. In research conducted at the School of Medicine, the unusual mixture inhibited the growth of aggressive prostate tumors in laboratory mice.

Unusual three-drug combo inhibits growth of aggressive tumors

An experimental anti-cancer regimen combined a diuretic, a Parkinson’s disease medication and a drug ordinarily used to reverse the effect of sedatives. In research conducted at Washington University School of Medicine in St. Louis, the unusual mixture inhibited the growth of aggressive prostate tumors in laboratory mice.

Researchers find ways heat-loving microbes release energy

Jan Amend sampling shallow marine vent fluids in 2005 at Ambitle Island, Papua, New Guinea.Curiosity about the microbial world drove Jan Amend, Ph.D., associate professor of earth and planetary sciences in Arts & Sciences at Washington University in St. Louis, to Vulcano Island, Italy, a shallow hydrothermal Shangri-la near Sicily. There, Amend and his collaborators managed to examine the environment in depth, design a gene probe, and discover new life-which could have some big implications for the origin and presence of life on Earth. More…