Study compares long-term effectiveness of diabetes drugs

Researchers at the School of Medicine are comparing the long-term benefits and risks of four widely used diabetes drugs given in combination with metformin, the most commonly prescribed medication for treating type 2 diabetes. The principal investigator at the St. Louis clinical site is Janet B. McGill, MD, who is pictured discussing options with study patient Michael Gingrich.

Diabetes drugs affect hearts of men, women differently

Widely used treatments for type 2 diabetes have different effects on the hearts of men and women, even as the drugs control blood sugar equally well in both sexes, according to researchers at the School of Medicine. The investigators used PET scans to measure heart and whole-body metabolism in patients taking common diabetes drugs. Pictured are researchers Janet B. McGill, MD, and Robert J. Gropler, MD.

Two drugs better than one to treat youth with type 2 diabetes

A combination of two diabetes drugs was more effective in treating 10-17-year-olds with recent-onset type 2 diabetes than one, according to researchers at Washington University in St. Louis who participated in a multicenter clinical trial funded by the National Institutes of Health (NIH). The Washington University School of Medicine segment of the trial was led by Neil H. White, professor of pediatrics and of medicine and director of the Pediatric Clinical Research Unit and a diabetes specialist at St. Louis Children’s Hospital.