Michael R. Bruchas

To better understand and one day provide improved treatments for depression, addiction and anxiety, School of Medicine researchers are using tiny, electronic devices to identify and map neural circuits in the brain. The work has been awarded a rare grant called EUREKA (Exceptional, Unconventional Research Enabling Knowledge Acceleration), which provides funding for high-risk/high-reward projects.

Using a miniature electronic device implanted in the brain, scientists have tapped into the internal reward system of mice, prodding neurons to release dopamine, a chemical associated with pleasure. This LED light can activate brain cells and may lead to the mapping of circuits involved in sleep, depression and addiction.

Andrew Yoo, Robert Gereau and Michael Bruchas have been awarded grants from the National Institues of Health Common Fund to pursue visionary research that has the potential to transform science and improve human health.