Exploring the genomes of mice and men
New research by Ting Wang, PhD, (left) and graduate student Vasavi Sundaram has uncovered some striking differences in the genomes of humans and mice that can help scientists determine when a mouse may be a good stand-in to study human biology and disease.
Alzheimer’s plaques disrupt brain networks
Scientists studying the way Alzheimer’s disease takes root in
the brain have identified important new similarities between a mouse
model and human Alzheimer’s. Researchers at Washington University School of Medicine in St. Louis
have shown that brain plaques in mice are associated with disruption of
the ability of brain regions to network with each other.