Mouse cancer genome unveils genetic errors in human cancers
By sequencing the genome of a mouse with cancer, researchers at the School of Medicine have uncovered mutations that also drive cancer in humans.
Mouse model paves way for lung cancer studies
Lung tumors from mutant mice show an abundance of abnormal, undifferentiated cells.Often mice are used to investigate cancer because their accelerated life spans allow discoveries to be made in a few months. But most strains of mice stay relatively free of lung tumors, even when exposed to heavy tobacco smoke, so there has been a shortage of models suitable for studying tobacco smoke-induced lung cancer. Now, cancer researchers at the School of Medicine have developed a strain of mice that readily develops lung tumors that have the same genetic mutations found in human lung tumors.
Mouse model paves way for lung cancer studies
Lung tumors from mutant mice show an abundance of abnormal, undifferentiated cells.Often mice are used to investigate cancer because their accelerated life spans allow discoveries to be made in a few months. But most strains of mice stay relatively free of lung tumors, even when exposed to heavy tobacco smoke, so there has been a shortage of models suitable for studying tobacco smoke-induced lung cancer. Now, cancer researchers at Washington University School of Medicine in St. Louis have developed a strain of mice that readily develops lung tumors that have the same genetic mutations found in human lung tumors.