Brain cell activity regulates Alzheimer’s protein​

Increased brain cell activity boosts brain fluid levels of a protein linked to Alzheimer’s disease, according to new research from scientists at the School of Medicine. Senior author David M. Holtzman, MD, said the findings should help advance efforts to treat Alzheimer’s and other neurodegenerative disorders associated with the tau protein.​

Alzheimer’s protein detected in brain fluid of healthy mice

One of the most promising markers of Alzheimer’s disease, previously thought  only to be inside nerve cells, now appears to be normally released from nerve cells throughout life, according to researchers at Washington University School of Medicine in St. Louis.

Researchers identify genetic marker of aggressive Alzheimer’s disease

An international team of Alzheimer’s disease experts, led by Washington University School of Medicine in St. Louis, has uncovered a gene variation that appears to predict the rate at which Alzheimer’s disease will progress. Whereas previous studies have focused on factors that influence the risk for developing Alzheimer’s, the new research points to a way to determine how rapidly the disease will progress.