Proposed federal budget cuts to two major programs could translate into fewer treatments, fewer cures, fewer drug findings, fewer researchers and fewer breakthroughs in areas where the United States is a world leader, say science and health experts at Washington University in St. Louis.
In real estate, location is key. It now seems the same concept holds true when it comes to stopping pain. New research co-led by the School of Medicine indicates the location of receptors that transmit pain signals is important in how big or small a pain signal will be and how effectively drugs can block those signals.
Many negative consequences are linked to growing up poor, and researchers at Washington University St. Louis have identified one more: altered brain connectivity.
New research from Washington University in St. Louis has identified a novel learning and memory brain network that processes incoming information based on whether it’s something we’ve experienced previously or is deemed to be altogether new and unknown, helping us recognize, for instance, whether the face before us is that of a familiar friend or a complete stranger.
Calming a neural circuit in the brain can alleviate stress in mice, according to new research at Washington University School of Medicine in St. Louis that lays the foundation for understanding stress and anxiety in people. The researchers also showed they could shine a light into the brain to activate the stress response in mice that had not been exposed to stressful situations.
A team of researchers, including neuroscientists from Washington University School of Medicine in St. Louis, has developed a wireless device the width of a human hair that can be implanted in the brain and activated by remote control to deliver drugs to brain cells. The technology, demonstrated for the first time in mice, one day may be used to treat pain, depression, epilepsy and other neurological disorders in people by targeting therapies to specific brain circuits.
In an effort to increase diversity in the neurosciences, Washington University in St. Louis has received a five-year, $1.5 million federal grant to participate in a national pipeline program with that mission.
In 1999, Danish scientist Per Bak made the startling proposal that the brain remained stable for much the same reason a sand pile does; many small avalanches hold it at a balance point, where — in the brain’s case — information processing is optimized. Now scientists have shown for the first time that a brain receiving and processing sensory input follows these dynamics.
Anesthesiology researchers Robert Gereau, PhD, (left) and Michael Bruchas, PhD, (right) have received one of only 11 DECODE (Deciphering Circuit Basis of Disease) grants to be awarded. The awards were announced at a ceremony featuring Thomas Insel, MD, (center) director of the National Institute of Mental Health (NIMH).
Marcus E. Raichle, MD, a Washington University professor internationally renowned for his contributions to advancing the frontiers of cognitive neuroscience, is one of three scientists awarded this year’s prestigious Kavli Prize in Neuroscience.