New research from David Gutmann, MD, PhD, may help doctors determine which medical issues are likely to manifest in patients with the inherited cancer syndrome neurofibromatosis type 1 (NF1). The findings indicate that varying mutations in the NF1 gene may lead to different clinical outcomes.
New insight into one of the most common inherited causes of brain tumors may help physicians diagnose and treat the learning disabilities that often accompany the condition, neurofibromotosis 1. The School of Medicine’s David H. Gutmann is the study’s senior author.
Scientists are eager to make use of stem cells’ extraordinary power to transform into nearly any kind of cell, but that ability also is cause for concern in cancer treatment. New research at the School of Medicine has revealed that these stem cells are present even in slow-growing, less aggressive tumors.
The causes of learning problems associated with an inherited brain tumor disorder are much more complex than scientists had anticipated, researchers at Washington University School of Medicine in St. Louis report.
Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.
The Washington University Neurofibromatosis (NF) Center at will host its first research symposium May 4. The event will focus on clinical and basic science research on neurofibromatosis 1, an inherited condition that increases risk of brain tumors in children and adults.
Scientists have developed a way to evaluate new treatments for some forms of attention deficit disorder. Working in mice, researchers at the School of Medicine showed that they can use brain scans to quickly test whether drugs increase levels of dopamine. The same group found that raising dopamine levels in mice alleviates attention deficits caused by neurofibromatosis type 1 (NF1), a condition that affects more than 100,000 people in the United States.
With support from a new $3.3 million American Recovery and Reinvestment Act grant from the National Institute of Neurological Disorders and Stroke, researchers at Washington University School of Medicine in St. Louis are hunting for normal cells that help brain tumors form and grow
A genetic condition that increases risk of brain tumors may also impair development of the brain system that facilitates attention, according to researchers at Washington University School of Medicine in St. Louis.
Nerve cells in the body and brain react in opposite ways to the loss of a protein linked to a childhood tumor syndrome, researchers at Washington University School of Medicine in St. Louis have found. The finding could be important to efforts to preserve the vision of patients with neurofibromatosis 1, a genetic condition that increases risk of benign and malignant brain tumors.