Winners of Bear Cub grants announced

Washington University’s Bear Cub program is funding four innovative projects that have commercial potential. Pictured is William G. Hawkins, MD, who is developing a new treatment for pancreatic cancer.

Brain-building gene plays key role in gut repair​​

A gene with a colorful name – mindbomb 1 – plays a key role far beyond the brain. New research at Washington University School of Medicine in St. Louis shows that mindbomb 1 may be involved in repairing cells injured by infection or inflammation in the stomach and pancreas. Researchers also found hints that mindbomb 1 may have connections to cancer in those organs.

HIV protein enlisted to help kill cancer cells

This PET scan shows high levels of an anticancer agent in the tumor.Cancer cells keep growing because they don’t react to internal signals urging them to die. Now researchers at the School of Medicine have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. And they did it using one of the most sinister pathogens around — HIV.

HIV protein enlisted to help kill cancer cells

Researchers linked anticancer agents to a PET tracer to deliver treatment directly to tumors in mice (red and yellow shows highest amounts of tracer).Cancer cells keep growing because they don’t react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. And they did it using one of the most sinister pathogens around — HIV.