Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study demonstrated that treating the parasite reduces lung damage seen in mice that also are infected with tuberculosis, thereby eliminating the vulnerability to tuberculosis (TB) that the parasite is known to cause.
Two new studies explain why some parasite infections, such as those common in developing countries, sometimes can’t be cured with standard treatments. The research shows the parasite Leishmania — which infects 12 million people worldwide — often harbors a virus that helps the parasite survive treatments.
Scientists may be able to entomb the malaria parasite in a prison of its own making, researchers at Washington University School of Medicine in St. Louis report July 16 in Nature.
Signals from the immune system that help repel a common parasite inadvertently can cause a dormant viral infection to become active again, a new study from the School of Medicine shows. Pictured is a helminth parasite.
A multi-institutional campaign to harness a newly recognized cellular defense against infection is being led by researchers at the School of Medicine. A $32 million grant from the National Institutes of Health is funding the collaborative, which could lead to drugs with unprecedented versatility in fighting different infections. Washington University’s Herbert W. Virgin IV, MD, PhD, is the principal investigator.
Scientists have decoded the DNA of the parasitic worm that causes trichinosis, a disease linked to eating raw or undercooked pork or carnivorous wild game animals, such as bear and walrus.
A parasite and a virus may be teaming up in a way that increases the parasite’s ability to harm humans, scientists at the University of Lausanne in Switzerland and Washington University School of Medicine in St. Louis report this week in Science.
Researchers at Washington University School of Medicine in St. Louis have learned why changes in a single gene, ROP18, contribute substantially to dangerous forms of the parasite Toxoplasma gondii. The answer has likely moved science a step closer to new ways to beat Toxoplasma and many other parasites.
Scientists battling Leishmania, a parasite second only to malaria in the number of deaths it causes, have identified an important vulnerability in the genetic code of one major parasite strain.
A parasite estimated to afflict as many as 12 million people worldwide relies on a family of genes that should make it vulnerable to compounds developed to treat cancer and other disorders, researchers at Washington University School of Medicine in St. Louis have found.