Scientists find ideal target for malaria therapy

Scientists at Washington University School of Medicine in St. Louis have identified a protein made by the malaria parasite that is essential to its ability to take over human red blood cells. “Without this protein … the infectious process stops,” says Dan Goldberg, M.D.

WUSTL receives $13 million Gates Foundation global health grant toward elimination of tropical diseases

Washington University School of Medicine in St. Louis has received a five-year, $13 million grant from the Bill & Melinda Gates Foundation to improve efforts to eliminate two parasitic diseases, elephantiasis and river blindness. The award is believed to be the largest global health grant so far to the University.

Sequenced parasite tells more about pathogen’s dirty work

Michael R. Brent and Tamara L. Doering examine data from the *C. neoformans* microarray.A team of collaborators, including two researchers from Washington University in St. Louis, has sequenced the genomes of two strains of the fungus Cryptococcus neoformans (C. neoformans), one which is virulent, the other harmless. This work provides researchers with clues on how the fungus does its dirty work and a host of genes to study for a better understanding of fungal pathogens in general. Estimates are that about 15 percent of people with HIV will suffer at least one life-threatening infection of C. neoformans. In Africa, that could be as much as 40 percent of HIV sufferers.