The Ebola virus, in the midst of its biggest outbreak on record, is a master at evading the body’s immune system. But researchers at the School of Medicine and elsewhere have learned one way the virus dodges the body’s antiviral defenses, providing important insight that could lead to new therapies.
Marco Colonna, MD, has been named the Robert Rock Belliveau, MD, Professor of Pathology at Washington University School of Medicine in St. Louis. Shown (from left) are Colonna; Belliveau’s wife, Rita Deanin Abbey; and Belliveau.
Researchers have identified the primary player of the biochemical bugle call that musters the body’s defenders against viral infection. Scientists at Washington University School of Medicine in St. Louis have shown that a key molecule, MDA5, is essential for producing enough interferon (the bugle call) to rally virus-fighting cells during certain viral infections.
Kenneth M. Murphy, MD, PhD, has been named the Eugene L. Opie First Centennial Professor of Pathology and Immunology at Washington University School of Medicine in St. Louis.