Alzheimer’s-like changes affect brains of elderly long before symptoms appear
Older adults with evidence of amyloid in the brain but no clinical symptoms of Alzheimer’s disease have structures in the brain that don’t communicate readily with each other, according to researchers at Washington University School of Medicine in St. Louis. The findings may be yet another indicator that Alzheimer’s damage to the brain begins to occur long before there are clinical symptoms of the disease.
Imaging technique detects plaques in Alzheimer’s disease
PET scans: normal (top 2 rows) and Alzheimer’s.After decades of searching, scientists finally may have identified a way to study Alzheimer’s disease changes in living human brains. Researchers at Washington University’s Alzheimer’s Disease Research Center (ADRC) have begun studies of an imaging agent developed at the University of Pittsburgh that could potentially detect amyloid plaques with a positron emission tomography (PET) scan, enabling earlier detection of the disease and improved testing of new treatments.