Relapse, poor survival in acute leukemia linked to genetic mutations that persist in remission
For patients with an often-deadly form of leukemia, new research by Timothy J. Ley, MD, and colleagues suggests that lingering cancer-related mutations – detected after initial treatment with chemotherapy – are associated with an increased risk of relapse and poor survival.
Chemotherapy may influence leukemia relapse
The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study suggest.