Schizophrenia symptoms linked to features of brain’s anatomy​​

Schizophrenia symptoms linked to features of brain’s anatomy​​

Using advanced brain imaging, researchers have matched certain behavioral symptoms of schizophrenia to features of the brain’s anatomy. The findings, from a research team led by the School of Medicine’s C. Robert Cloninger, MD, PhD, (shown) and Igor Zwir, PhD, could be a step toward improving diagnosis and treatment of schizophrenia.

New target explored for psychiatric drug development

In a surprising discovery, neuroscientists, led by a team from Washington University School of Medicine in St. Louis, have found that a molecule that is a breakdown product of cholesterol in the brain may be a target for developing new drugs to treat schizophrenia and other mental illnesses.

Research offers clues for dealing with anxiety, childhood depression, schizophrenia

Research is shedding new light on what happens in the brains of children and adults affected by clinical depression, anxiety disorders and schizophrenia, according to Washington University in St. Louis studies presented at a recent mental health symposium. The findings, which come as America celebrates Mental Health Awareness Month, point to new treatment options for preschool-aged children with significant clinical depression and for severely depressed adults who don’t respond to standard treatments, such as antidepressants and psychotherapy.

Memory study shows brain function in schizophrenia can improve

Deanna Barch (center) discusses brain imaging techniques used in the experiment, which used the functional magnetic resonance imaging (fMRI) machine (shown at right).When encouraged to use memorization strategies commonly employed by healthy individuals, people with schizophrenia can be helped to remember information just as well as their healthy counterparts, a process that in itself seems to spur a normalization of memory-related activities in the brains of people with schizophrenia, suggests new research from Washington University in St. Louis.

Memory study shows brain function in schizophrenia can improve with support, holds promise for cognitive rehabilitation

Deanna Barch (right), co-author of a memory study that used a functional magnetic resonance imaging machine (shown in the background) to monitor the brain activity of people with schizophrenia.When encouraged to use memorization strategies commonly employed by healthy individuals, people with schizophrenia can be helped to remember information just as well as their healthy counterparts, a process that in itself seems to spur a normalization of memory-related activities in the brains of people with schizophrenia, suggests new research from Washington University in St. Louis.

Brain region learns to anticipate risk, provides early warnings, suggests new study in Science

Joshua Brown of WUSTLA new theory suggests that the brain may subconsciously help us avoid risky situations.While some scientists discount the existence of a sixth sense for danger, new research from Washington University in St. Louis has identified a brain region that clearly acts as an early warning system — one that monitors environmental cues, weighs possible consequences and helps us adjust our behavior to avoid dangerous situations. “Our brains are better at picking up subtle warning signs than we previously thought,” says WUSTL research psychologist Joshua Brown, co-author of a study on these findings in the Feb. 18 issue of the journal Science.

Brain region learns to anticipate risk, provides early warnings, suggests new study in Science

Joshua Brown of WUSTLA new theory suggests that the brain may subconsciously help us avoid risky situations.While some scientists discount the existence of a sixth sense for danger, new research from Washington University in St. Louis has identified a brain region that clearly acts as an early warning system — one that monitors environmental cues, weighs possible consequences and helps us adjust our behavior to avoid dangerous situations. “Our brains are better at picking up subtle warning signs than we previously thought,” says WUSTL research psychologist Joshua Brown, co-author of a study on these findings in the Feb. 18 issue of the journal Science.
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