Lung cancer study hints at new treatments

Studying the most common type of lung cancer, researchers from The Cancer Genome Atlas have uncovered new mutations in a cell-signaling pathway that plays a role in forming tumors. The new knowledge may expand treatments for patients because drugs targeting some of these genetic changes already are available or are in clinical trials.

Genomics to reshape endometrial cancer treatment

The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women. The new research is published in the journal Nature. Pictured are endometrial cancer cells under a microscope.

Large lung cancer study shows potential for more targeted therapies

A nationwide consortium of scientists has reported the first comprehensive genetic analysis of squamous cell carcinoma of the lung, a common type of lung cancer responsible for about 400,000 deaths each year. According to Ramaswamy Govindan, MD, of Washington University School of Medicine in St. Louis, about 75 percent of the tumors studied have mutations that can be targeted with existing drugs.