Proton beam accelerator installation under way

Workers unwrap the world’s first superconducting synchrocyclotron proton accelerator at the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis. The device is part of a proton therapy system being installed at Washington University Medical Center at the Kling Center for Proton Therapy,

DNA of 50 breast cancer patients decoded

In the single largest cancer genomics investigation reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients’ healthy cells. They uncovered incredible complexity in the cancer genomes, but also got a glimpse of new routes toward personalized medicine.

Pathway toward gene silencing described in plants

Olga Pontes is Going FISHin’.Biologists at Washington University in St. Louis have made an important breakthrough in understanding a pathway plant cells take to silence unwanted or extra genes using short bits of RNA. Basically, they have made it possible to see where, and how, the events in the pathway unfold within the cell, and seeing is believing, as the old saying goes. Craig Pikaard, Ph.D., Washington University professor of biology in Arts & Sciences and his collaborators have described the roles that eight proteins in Arabidopsis plants play in a pathway that brings about DNA methylation, an epigenetic function that involves a chemical modification of cytosine, one of the four chemical subunits of DNA. More…