turn on

Olga Pontes & Craig PikaardThe protein HDA6 shows up as a red stain in this Arabidopsis leaf cell nucleus.A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off — in this case, the turning off of thousands of nearly identical genes in a hybrid plant. Studying the phenomenon of nucleolar dominance, in which one parental set of ribosomal genes in a hybrid is silenced, Craig Pikaard, Ph.D., Washington University professor of biology in Arts & Sciences and colleagues have identified the protein HDA6 as an important player in the silencing. More…