Less of a shock

Two scientists at Washington University have developed a low-energy defibrillation scheme that significantly reduces the energy needed to re-establish a normal rhythm in the heart’s main chambers. They hope this electrotherapy will be much less painful than the existing electrotherapy, making treatment with a defibrillator much more acceptable to patients.

Dangerous arrhythmia analyzed in a heartbeat

Just one second, one heartbeat. That’s what is needed for a new, noninvasive functional imaging technology, developed by a Washington University in St. Louis scientist, to record data for locating the source in the heart of a dangerous cardiac arrhythmia called ventricular tachycardia (VT). WUSTL researchers in biomedical engineering and medicine report in the Aug. 31, 2011, issue of Science Translational Medicine, that the technique would far more quickly find the source and type of VT, saving hours of mapping.  

Heart failure linked to altered communication channels

Bright areas in this image highlight the junctions between heart muscle cells.Failing hearts develop interference in their communication channels, according to research conducted at the School of Medicine. The problem involves a subtle change in the pores that connect heart muscle cells. When the scientists duplicated this change in mice, the mice became susceptible to ventricular tachycardia, a dangerous heart rhythm disorder that can lead to sudden cardiac death.

Heart failure linked to altered communication channels

Bright areas in this image highlight the junctions between heart muscle cells.Failing hearts develop interference in their communication channels, according to research conducted at Washington University School of Medicine in St. Louis. The problem involves a subtle change in the pores that connect heart muscle cells. When the scientists duplicated this change in mice, the mice became susceptible to ventricular tachycardia, a dangerous heart rhythm disorder that can lead to sudden cardiac death.