Antibiotics: Thinking outside the vial

Antibiotics: Thinking outside the vial

Given that antibiotics are losing effectiveness faster than we are finding replacements for them, chemist Timothy Wencewicz in Arts & Sciences at Washington University in St. Louis suggests a new approach. Drugs that hobble the production of virulence factors — small molecules that help bacteria to establish an infection in a host — would put much less selective pressure on bacteria and delay resistance.