A new test efficiently detects virtually any virus that infects people and animals, according to research at Washington University School of Medicine, where the technology was developed.
Two new studies explain why some parasite infections, such as those common in developing countries, sometimes can’t be cured with standard treatments. The research shows the parasite Leishmania — which infects 12 million people worldwide — often harbors a virus that helps the parasite survive treatments.
Antibiotics aren’t supposed to be effective against viruses, but new evidence in mice suggests they may help fight norovirus, a highly contagious virus that causes severe gastrointestinal illness, scientists at the School of Medicine report.
The same viruses that make us sick can take up residence in and on the human body without provoking a sneeze, cough or other troublesome symptom, according to new research at Washington University School of Medicine in St. Louis.
The Ebola virus, in the midst of its biggest outbreak on record, is a master at evading the body’s immune system. But researchers at the School of Medicine and elsewhere have learned one way the virus dodges the body’s antiviral defenses, providing important insight that could lead to new therapies.
Scientists at the School of Medicine have produced the first detailed images of a protein important to viral infection. The images, from Phyllis Hanson, MD, PhD, and her colleagues, are of molecular scissors that let viruses such as HIV bud from infected cells.
A multi-institutional campaign to harness a newly recognized cellular defense against infection is being led by researchers at the School of Medicine. A $32 million grant from the National Institutes of Health is funding the collaborative, which could lead to drugs with unprecedented versatility in fighting different infections. Washington University’s Herbert W. Virgin IV, MD, PhD, is the principal investigator.
Researchers have shown they can distinguish between viral and bacterial infections in children with fever by profiling the activity of genes in a blood sample.
Scientists at Washington University School of Medicine in St. Louis have identified the molecular signal that triggers the development of immune cells that patrol the skin and brain.
Researchers have identified the primary player of the biochemical bugle call that musters the body’s defenders against viral infection. Scientists at Washington University School of Medicine in St. Louis have shown that a key molecule, MDA5, is essential for producing enough interferon (the bugle call) to rally virus-fighting cells during certain viral infections.