Warfarin no better than aspirin for most heart failure patients

Results of one of the largest studies of heart failure to date show that warfarin is no better than aspirin in reducing the combined risks of brain hemorrhage, stroke and death in most heart failure patients. Clinicians now have reassurance that aspirin is safe for heart failure patients with a normal heart rhythm, according to study co-author Douglas L. Mann, MD.

$3.7 million trial uses genes to balance risks, benefits of blood thinner

A five-year, $3.7 million clinical trial will investigate how to balance the benefits and risks of warfarin, a drug that helps prevent potentially deadly blood clots. The multicenter study, led by researchers at Washington University School of Medicine in St. Louis, will evaluate customized warfarin dosage based on patient genetics and will test which range of blood clotting is optimal in orthopedic patients.