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Marcus E. Raichle, MD, has been named an inaugural Alan A. and Edith L. Wolff Distinguished Professor of Medicine at the School of Medicine. A professor of radiology, psychology, biomedical engineering, neurobiology and neurology, his many honors include the 2014 Kavli Prize for Neuroscience.

Marcus E. Raichle, MD, a Washington University professor internationally renowned for his contributions to advancing the frontiers of cognitive neuroscience, is one of three scientists awarded this year’s prestigious Kavli Prize in Neuroscience.

A boost in the speed of brain scans is unveiling new insights into how brain regions work with each other in cooperative groups called networks. Shown is the study’s senior researcher, Maurizio Corbetta, MD.

Scientists at Washington University School of Medicine in St. Louis have taken one of the first detailed looks into how Alzheimer’s disease disrupts coordination among several of the brain’s networks.

When it comes to communication in the brain, more is usually better. But now scientists, including Maurizio Corbetta, MD, have linked increased communication in a network of brain regions to more severe mental impairment in patients with early-stage multiple sclerosis (MS).

Higher levels of cellular chatter boosts levels of amyloid beta in the brain regions that Alzheimer’s hits first, researchers at Washington University School of Medicine in St. Louis report. Amyloid beta is the main ingredient of the plaque lesions that are a hallmark of Alzheimer’s. The finding may help explain why areas that are most active when the brain rests are often among the first to develop these plaques, according to the researchers.

Marcus E. Raichle, MD, professor of radiology, of neurobiology and of neurology in the School of Medicine, received a MetLife Foundation Award for Medical Research in Alzheimer’s Disease Feb. 24 in New York. Raichle has been producing brain imaging research contributing to the way Alzheimer’s is now diagnosed and treated for nearly 40 years.

People with a known, high risk for Alzheimer’s disease develop abnormal brain function even before the appearance of telltale, amyloid plaques that are characteristic of Alzheimer’s disease, according to a new study from researchers at Washington University School of Medicine in St. Louis. The findings suggest that a gene variant affects brain function long before the brain begins accumulating the amyloid that will eventually lead to dementia.