Genes linked to Alzheimer’s risk, resilience ID’d

Genes linked to Alzheimer’s risk, resilience ID’d

A team led by researchers at the School of Medicine in St. Louis has identified a pair of genes that influence risk for Alzheimer’s disease. The genes — known as MS4A4A and TREM2 — affect the brain’s immune cells. They influence Alzheimer’s risk by altering levels of TREM2, a protein that is believed to help microglia cells clear excessive amounts of the Alzheimer’s proteins amyloid and tau from the brain.
Siteman Cancer Center awarded $7.8 million to expand clinical trials access

Siteman Cancer Center awarded $7.8 million to expand clinical trials access

Physicians at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis have been awarded a six-year, $7.8 million grant from the National Cancer Institute (NCI) to play a leading role in designing, conducting and enrolling patients in clinical trials through the NCI’s National Clinical Trials Network.
Goal-oriented rehab improves recovery in older adults

Goal-oriented rehab improves recovery in older adults

Researchers at the School of Medicine have found that Enhanced Medical Rehabilitation, a type of goal-oriented therapy, helps older patients recover more fully than standard physical or occupational therapy. It involves focusing on specific goals important to individual patients and motivating patients to work toward those goals during every therapy session.
Genes linked to death from sepsis ID’d in mice

Genes linked to death from sepsis ID’d in mice

Bacteria in the bloodstream can trigger an overwhelming immune response that causes sepsis, a life-threatening condition. Now, researchers at Washington University School of Medicine in St. Louis have found genes that help protect the body’s cells from dying during sepsis, which could lead to new treatments.
More cancer patients get help to quit smoking

More cancer patients get help to quit smoking

A new program funded through the Cancer Moonshot Initiative has doubled the number of patients at Siteman Cancer Center assessed for smoking — and increased by fivefold the percentage of cancer patients who smoke now taking medication to help them quit. The results have been published in the journal Translational Behavioral Medicine.
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