Typhoid fever genomes to help scientists seek better vaccines

Salmonella entericaEvery year in developing nations, typhoid fever infects more than 16 million people and kills more than half a million. Researchers hoping to reduce this heavy toll have an important new tool: completed genomes for the two bacteria that are the leading causes of typhoid fever.

Alcohol-Induced blackouts may be genetic

Heavy drinking is associated with a number of problems, but one surprisingly common problem involves not remembering large chunks of time. Called alcohol-induced blackouts, these memory losses were reported by more than 39 percent of women and more than 50 percent of men studied by researchers from Washington University School of Medicine in St. Louis and the Queensland Institute on Medical Research in Australia. The researchers also found that genetic factors play a big role in whether or not a person blacks out after heavy drinking. Studying more than 2,300 pairs of Australian twins, the research team was able to determine that more than 50 percent of the risk of blacking out seems to be controlled by genetic factors, and the role of genes is even greater in people who report blacking out multiple times.

Renowned historian of life and biomedical sciences to give Thomas Hall Lecture

Everett Mendelsohn, one of America’s foremost historians of science, will deliver the Thomas Hall Lecture titled “Dolly and the Historians: Science, Politics and Ethics of Cloning” as part of the Washington University Assembly Series at 4 p.m., Thursday, November 13. The lecture is free and open to the public and will be held in Rebstock Hall, Room 215, located just east of Mallinckrodt Center (6445 Forsyth Blvd) on the Washington University campus.

Nobel Prize recipient Sydney Brenner to discuss ‘Humanity’s Genes’

Nobel Prize-winning biologist Sydney Brenner will deliver the annual Arthur Holly Compton Memorial Lecture for the Assembly Series at 4 p.m. Tues, Oct. 14. The lecture,”Humanity’s Genes,” is free and open to the public and will be held in Graham Chapel, located just north of Mallinckrodt Center (6445 Forsyth Blvd.) on the Washington University campus. Brenner’s lecture will discuss some of the questions raised by the completion of the Human Genome Project. He will talk about both the benefits and the fears raised by recent breakthroughs in genetic research, and his belief that the brain is mightier than the genome.