Fat signals control energy levels in the brain

Fat signals control energy levels in the brain

An enzyme secreted by the body’s fat tissue controls energy levels in the brain, according to new research led by Shin-ichiro Imai, MD, PhD, of the School of Medicine. The findings, in mice, underscore a role for the body’s fat tissue in controlling the brain’s response to food scarcity, and suggest there is an optimal amount of body fat for maximizing health and longevity.

Aging and longevity tied to specific brain region in mice

The protein SIRT1 in the brain is tied into a mechanism that allows animals to survive when food is scarce, according to a new study at Washington University School of Medicine in St. Louis. The research suggests that SIRT1 may be involved with the life span-increasing effect of low-calorie diets, they report.