A new study in mice suggests that gene therapy may one day be a viable treatment for Alport syndrome, an inherited disease that leads to kidney failure.
Washington University in St. Louis has awarded five Bear Cub fund grants totaling $190,000 to support innovative research that has shown commercial potential. Jerry Morrissey (right), PhD, received one of the grants to develop rapid tests for the early development of kidney cancer.
Giving children intravenous fluids early in the course of an E. coli O157:H7 infection appears to lower the odds of developing severe kidney failure, according to Christina Ahn Hickey, MD, and other researchers at Washington University School of Medicine in St. Louis and other institutions.
Red blood cells damaged by inflammation caused by food poisoning.A protein that helps keep immune system cells from mistakenly swallowing and destroying healthy cells has been linked to an inherited disorder with symptoms similar to severe food poisoning, according to researchers at the Washington University School of Medicine and the University of Newcastle in the United Kingdom. John Atkinson, M.D., the Samuel Grant Professor of Medicine at Washington University School of Medicine in St. Louis, says the results make it possible to genetically screen patients for one form of atypical hemolytic uremic syndrome (HUS), a rare but potentially life-threatening condition linked to excessive cell damage, blood clots and kidney failure. Normal HUS, often in the headlines because of food-related outbreaks, is caused by consumption of a toxic form of the bacteria E. coli.