Genes that promote cartilage healing protect against arthritis
New research from Washington University School of Medicine in St. Louis shows that the same genes that promote healing after cartilage damage also appear to protect against osteoarthritis, a condition caused by years of wear-and-tear on the cartilage between joints. Although the research was conducted in mice, the genes are likely to be important in people, too.
$3.7 million trial uses genes to balance risks, benefits of blood thinner
A five-year, $3.7 million clinical trial will investigate how to balance the benefits and risks of warfarin, a drug that helps prevent potentially deadly blood clots. The multicenter study, led by researchers at Washington University School of Medicine in St. Louis, will evaluate customized warfarin dosage based on patient genetics and will test which range of blood clotting is optimal in orthopedic patients.